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Symbol
Name
ID

Idh1
isocitrate dehydrogenase 1 (NADP+), soluble
MGI:96413

Phenotype annotations related to immune system

Darker colors indicate more annotations

Human Phenotypes	Acute myeloid leukemia	Autoimmunity	Autoimmune antibody positivity
Disease(s) Associated with IDH1	Acute myeloid leukemia	Autoimmunity	Autoimmune antibody positivity
acute myeloid leukemia
autoimmune disease

Mouse Phenotypes		enlarged spleen	decreased B cell number	decreased CD4-positive, alpha-beta T cell number	increased CD4-positive, alpha-beta T cell number	decreased CD8-positive, alpha-beta T cell number	abnormal spleen morphology
Availability	Mouse Genotype	enlarged spleen	decreased B cell number	decreased CD4-positive, alpha-beta T cell number	increased CD4-positive, alpha-beta T cell number	decreased CD8-positive, alpha-beta T cell number	abnormal spleen morphology
	Idh1^tm1Mak/Idh1^tm1Mak Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)
	Idh1^tm2Mak/Idh1^tm2Mak Lyz2^tm1(cre)Ifo/Lyz2⁺ (conditional)

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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